The human herpesvirus-type 8 is not involved in malignant melanoma
نویسندگان
چکیده
منابع مشابه
A review on human herpesvirus type 8 infection 8
Volume 11 Number 2, Summer 2003 A review on human herpesvirus type 8 infection 8 PKS Chan , RCW Chan Human herpesvirus type eight (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV) is the most recently identified human herpesvirus. Over the last decade, many studies have focused on the epidemiology and disease association of this novel virus. It is aetiologically associated w...
متن کاملRegulation of interleukin 8 expression in human malignant melanoma cells.
Here, we report the molecular regulation of interleukin (IL)-8 expression in human melanoma cells. The inflammatory cytokines IL-1beta and tumor necrosis factor-alpha (TNF-alpha) up-regulated IL-8 expression, in a time- and concentration-dependent manner, in three metastatic melanoma variants, SBC-2 (nonmetastatic), A375P (low metastatic), and A375SM (high metastatic), by increased transcriptio...
متن کاملEpidemiology of Human Herpesvirus Type 8 Infection in Cardiopathic Patients
Problem statement: The possible contribution of viruses to vascular pathology is still a controversial issue. Human herpesvirus type 8 (HHV-8) has been suggested to participate to the pathogenetic events associated with atherosclerotic lesion establishment and progression. Recently, a high incidence of infection of HHV-8 (11%) has been verified in the island of Sardinia. The aim of this study w...
متن کاملHuman herpesvirus type 8 in tuberculosis patients with effusion
BACKGROUND Many patients with tuberculosis (TB) are seropositive for human herpesvirus type 8 (HHV-8), and many patients with primary effusion lymphoma have high levels of HHV-8 DNA in their effusions. However, the status of HHV-8 in the effusions of patients with TB remains unclear. METHODS Blood samples were collected from 129 patients with pulmonary TB and 129 age- and sex-matched healthy ...
متن کاملHuman herpesvirus type 8 interleukin-6 homologue is functionally active on human myeloma cells.
Seroepidemiology and polymerase chain reaction studies have strongly suggested that human herpesvirus type 8 (HHV-8) is associated with Kaposi's sarcoma, Castleman's disease, and body cavity-based lymphoma. The genome of HHV-8 harbors a viral analogue of the interleukin-6 (IL-6) gene. The amino acid sequence of the viral IL-6 (vIL-6) protein is 24.7% identical to human IL-6 (hIL-6). IL-6 as a B...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1999
ISSN: 0007-0920,1532-1827
DOI: 10.1038/sj.bjc.6690322